Gel electrophoresis: The applications and its improvement with nuclear technology

Gel electrophoresis is a standardized technique that routinely used in many daily needs, such as clinical laboratories, forensic and industry, molecular biology biochemistry, conservational biology, medicine. This paper reviews several types of techniques, with two mostly being agarose acrylamide gel electrophoresis, either isotopic or non-isotopic based analysis. exploits the difference size charge various molecules sample analyzed. An example application to detect presence quantitatively qualitatively abnormal protein bands. Alterations relative concentration fractions allow easy recognition pathological disorders associated disease. In food it applied safeguard quality products. The advantages this are also described simple, sensitive, short analysis time, low cost, environment friendly. range its modification continues expand. Here, an radioisotope labeled 50 drug resistance tuberculosis bacteria had been done showed samples altered DNA mobility shift on related specific gene mutation. Nuclear has shown improvement relatively more sensitive compared conventional one but high risk. It can be concluded proven most useful versatile techniques biological sciences research.